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View a PDF of the paper titled Flip Distance of Triangulations of Convex Polygons / Rotation Distance of Binary Trees is NP-complete, by Joseph Dorfer
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In 1996, David Deamer and Daniel Branton’s labs at UC Santa Cruz and Harvard collaborated on a paper showing that when an electric current runs through a nanopore, passing purine (A and G) and pyrimidine (T and C) DNA bases through the nanopore disrupted the current to different degrees. While the technique couldn’t yet discriminate between all four bases, the general idea for a new single-molecule sequencing method was there.，更多细节参见clash下载